Equine Molecular Genetics

Our Research

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Collaborative Research

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Research Priorities

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Current Projects

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Publications

2022

list of publications

2021

  • Tillquist, Nicole Mary-Belle, Thorndyke, Meghan Paige, Thomas, Tyler, Coleman, Stephen John, Engle, Terry E, (2021) Impact of Cell Culture and Copper Dose on Gene Expression in Bovine Liver Biological Trace Element Research

2020

  • Pierce, Courtney F, Speidel, Scott E, Coleman, Stephen John, Enns, R Mark, Bailey, Derek W, Medrano, Juan F, Canovas, A, Meiman, Paul, Howery, Larry D, Mandeville, Walter F, Thomas, Milt, (2020) Genome-wide association studies of beef cow terrain-use traits using Bayesian multiple-SNP regression. Livestock Science

  • Twenter, Hannah, Klohonatz, Kristin M, Davis, Kelly, Bass, Luke Daniel, Coleman, Stephen John, Bouma, Gerrit J, Bruemmer, Jason, (2020) MicroRNA delivered to stallion spermatozoa: Epididymosomes transfer microRNAs from epididymal epithelium to equine spermatozoa. Journal of Equine Veterinary Science
  • Coleman, Stephen John, Petersen, Jessica L, (2020) Next-Generation Sequencing in Equine Genomics Veterinary Clinics of North America – Equine Practice
  • Carver, Clarissa Margaret, Hess, Tanja, Bruemmer, Jason, Coleman, Stephen John, Landolt, Gabriele A, (2020) “Effects of Corn Supplementation on Serum and Muscle MicroRNA Profiles Within Horses” 20TH ANNUAL AAVN CLINICAL NUTRITION & RESEARCH SYMPOSIUM 20 14
  • Wilson, L, Jennings, Kaysie, Coleman, Stephen John, “Gene expression profiling of the pelvic flexure and surrounding large colon in the equine gastrointestinal tract by RNA-sequencing.” Plant and Animal Genome XXVIII
  • Crawford, Natalie Faye, Jennings, Kaysie, Canovas, Angela, Medrano, Juan F., Islas-Trejo, A., Brown, R. D., Coleman, Stephen John, Speidel, Scott E, Enns, Mark Mark, Stenmark, Kurt R., Thomas, Milt, (2020) “Genes regulating calcium availability and utilization in Angus steers may be useful in identifying cattle with reduced susceptibility to pulmonary hypertension in high altitude beef production systems.” Plant and Animal Genome XXXVII Conference PO0369
  • Pierce, C.F., Speidel, Scott E, Coleman, Stephen John, Enns, Mark Mark, Bailey, D.W., Medrano, J.F., C\’anovas, A., , Meiman, P.J., Howery, L.D., Mandeville, W.F., Thomas, Milt, (2020) Genome-Wide Association Studies of Beef Cow Terrain-Use Traits Using Bayesian Multiple-SNP Regression Livestock Science 232 103900
  • Pierce, Courtney Fay, Speidel, Scott E, Coleman, Stephen John, Enns, Mark Mark, Bailey, Derek, Medrano, Juan, Canovas, Angela, Meiman, Paul, Howery, Larry, Mandeville, Walter F., Thomas, Milt, (2020) Genome-wide association studies of beef cow terrain-use traits using Bayesian multiple-SNP regression Livestock Science 232 1-10

2010-2019

  • Jennings, K.J., Krafsur, G.M., Brown, R.D., Holt, Timothy N, Coleman, Stephen John, Speidel, Scott E, Enns, Mark Mark, Stenmark, K.R., Thomas, Milt, (2019) Characterizing the impact of altitude and finishing system on mean pulmonary arterial pressure and carcass characteristics in Angus cattle Translational Animal Science 3 Supplement\_1 1669-1672
  • Carver, Clarissa, Hess, Tanja, Bruemmer, Jason, Coleman, Stephen, Landolt, Gabiriele, (2019) “Effects of corn supplementation on muscle microRNA profiles within horses” Journal of Animal Science 97 supplement 3 310-311
  • Kunz, Isabelle G, Reed, Kailee Janelle, Metcalf, Jess Lynne, Hassel, Diana M, Coleman, Robert J, Hess, Tanja, Coleman, Stephen John, (2019) Equine fecal microbiota changes associated with anthelmintic administration Journal of Equine Veterinary Science 77 98-106
  • Jennings, Kaysie, Krafsur, Greta M, Brown, R D, Holt, Timothy N, Coleman, Stephen John, Speidel, Scott E, Enns, R M, Stenmark, K R, Thomas, Milt, (2019) Characterizing the impact of altitude and finishing system on mean pulmonary arterial pressure and carcass characteristics in Angus cattle. Translational animal science 3 Suppl 1 1669-1672
  • Klohonatz, Kristin Marie, Coleman, Stephen John, Cameron, A D, Hess, Ann Marie, Reed, Kailee Janelle, Canovas, A, Medrano, J F, Islas-Trejo, A D, Kalbfleisch, T, Bouma, Gerrit J, Bruemmer, Jason, (2019) Non-Coding RNA Sequencing of Equine Endometrium During Maternal Recognition of Pregnancy. Genes 10 10
  • Klohonatz, Kristin Marie, Coleman, Stephen John, Islas-Trejo, A D, Medrano, J F, Hess, Ann Marie, Kalbfleisch, T, Thomas, Milt, Bouma, Gerrit J, Bruemmer, Jason, (2019) Coding RNA Sequencing of Equine Endometrium during Maternal Recognition of Pregnancy. Genes 10 10
  • Klohonatz, Kristin Marie, Islas-Trejo, Alma D, Medrano, Juan F, Hess, Ann Marie, Coleman, Stephen John, Thomas, Milt, Bouma, Gerrit J, Bruemmer, Jason, (2018) “Evaluation of Equine Endometrium during Maternal Recognition of Pregnancy Utilizing RNA Sequencing” Journal of Equine Veterinary Science 66 222
  • Crawford, Natalie Faye, Coleman, Stephen John, Holt, Timothy N, Speidel, Scott E, Enns, Mark Mark, Hamid, R, Thomas, Milt, (2018) Allele distribution and testing for association between an oxygen dependent degradation domain SNP in EPAS1 and pulmonary arterial pressures in yearling Angus cattle Agri Gene 9 27-31
  • Crawford, Natalie Faye, Coleman, Stephen John, Enns, Mark Mark, Speidel, Scott E, Garry, Franklyn B, Holt, Timothy N, Thomas, Milt, (2018) “Pathway analyses revealed up-regulation of calcium-dependent genes in the cardiac right ventricle of Angus steers fed at high altitude” Journal of Animal Science 96 (Suppl 3) 61-62
  • Jennings, Kaysie, Krafsur, Greta M, Brown, D, Holt, Timothy N, Coleman, Stephen John, Speidel, Scott E, Enns, Mark Mark, Stenmark, K, Thomas, Milt, (2018) “Pulmonary hypertension in Angus steers: influence of finishing systems and altitudes” Journal of Animal Science 96 (Suppl 3) 87-87
  • Pierce, Courtney Fay, Bailey, D, Medrano, J, Cánovas, A, Speidel, Scott E, Coleman, Stephen John, Enns, Mark Mark, Thomas, Milt, (2018) “Validation of Quantitative Trait Loci Associated with Grazing Distribution Traits in Beef Cattle Using Bayes C” Journal of Animal Science 96 (Suppl 3) 105-105
  • Pierce, Courtney Fay, Bailey, D.W., Medrano, J.F., Cánovas, A., Speidel, Scott E, Coleman, Stephen John, Enns, Mark Mark, Thomas, Milt, (2018) “Characteristics of grazing distribution traits in beef cattle for genotype-phenotype associations” Proc. 11th World Congr. Genet. Appl. Livest. Prod. 11 246
  • Pierce, Courtney Fay, Barbero, M.M., Bailey, D.W., Medrano, J.F., Cánovas, A., Speidel, Scott E, Coleman, Stephen John, Enns, Mark Mark, Thomas, Milt, (2018) “Studying grazing distribution of beef cattle using DNA technology” Proc. 71st Soc. Range Mgmt. Ann. Meet.
  • Thomas, Milt, Holt, Timothy N, Enns, Mark Mark, Speidel, Scott E, Coleman, Stephen John, Culbertson, Randie Marguerite, Jennings, Kaysie, Krafsur, Greta M, Crawford, Natalie Faye, Krehbiel, B.C., (2018) “Summary Breeding and Genetics: genetic study of adaptability of beef cattle to altitude” Colorado State University
  • Jennings, K.J., Zeng, Xi, Reverter, A., Holt, T.N., Coleman, Stephen John, Enns, R.M., Speidel, Scott E, Thomas, Milt, (2017) “Construction of an association weight matrix to identify SNP that play a role in performance of Angus cattle at higher elevations” J. Anim. Sci. 95(E. Supple. 4) 86
  • Crawford, Natalie Faye, Coleman, Stephen John, Holt, T.N., Speidel, Scott E, Enns, R.M., Newman, J.H., Hamid, R., Thomas, Milt, (2017) “Genotyping a SNP in the endothelial PAS domaincontaining protein 1 (EPAS1) gene: is it associated with mean pulmonary arterial pressures in yearling Angus cattle?” J. Anim. Sci. 95(E. Supple. 4) 87
  • Pierce, C.F., Dias, M.M., Bailey, D.W., Medrano, J.F., Canovas, A, Speidel, Scott E, Coleman, Stephen John, Enns, R.M., Thomas, Milt, (2017) “SNP discovery for QTL associated with grazing distribution in Angus cattle using RNA-Seq” J. Anim. Sci. 95(E. Supple. 4) 85
  • Dias, Marina M, Canovas, Angela, Mantilla-Rojas, C., Riley, David G, Luna-Nevarez, Pablo, Coleman, Stephen John, Speidel, Scott E, Enns, Mark Mark, Islas-Trejo, A, Medrano, Juan F, Moore, Steve , Fortes, Marina, Nguyen, Loan T., Venus, B., Diaz, Iara, Souza, F., Albuquerque, L, Thomas, Milt, Oliveria, H., (2017) SNP detection using RNA-sequences of candidate genes associated with puberty in cattle Genetics and Molecular Research 16 1 17
  • Dias, M M, Cánovas, A, Mantilla-Rojas, C, Riley, D G, Luna-Nevarez, P, Coleman, Stephen John, Speidel, Scott E, Enns, Mark Mark, Islas-Trejo, A, Medrano, J F, Moore, S S, Fortes, M R, Nguyen, L T, Venus, B, Diaz, I S, Souza, F R, Fonseca, L F, Baldi, F, Albuquerque, L G, Thomas, Milt, Oliveira, H N, (2017) SNP detection using RNA-sequences of candidate genes associated with puberty in cattle. Genetics and molecular research : GMR 16 1
  • Dias, M.M., Cánovas, A., Mantilla-Rojas, C., Riley, D.G., Luna-Nevarez, P., Coleman, Stephen John, Speidel, Scott E, Enns, R.M., Islas-Trejo, A., Medrano, J.F., Thomas, Milt, (2017) SNP detection using RNA-sequences of candidate genes associated with puberty in cattle Genet. Mol. Res. 16 1
  • Thomas, Milt, Coleman, Stephen John, Speidel, Scott E, Enns, Mark Mark, (2016) “Multi-omics data resources and use in genetic improvement of cattle growth and health” J. Anim. Sci. 94(E. Suppl. 5) E369-E370
  • Crawford, Natalie Faye, Zeng, Xi, Coleman, Stephen John, Holt, Timothy N, Speidel, Scott E, Enns, Mark Mark, Newman, John, Hamid, R., Thomas, Milt, (2016) “Pulmonary arterial pressure in yearling Angus cattle managed at high altitude: Study of a non-synonymous SNP in the oxygen-dependent degradation domain of the endothelial PAS domain-containing protein 1 gene” J. Anim. Sci. 94(E. Suppl. 5) E79-E80
  • Dias, M. M., Thomas, Milt, Canovas, A., Mantilla-Rojas, C., Riley, D., Luna, P., Coleman, Stephen John, Speidel, Scott E, Enns, Mark Mark, Ilas-Trejo, A., Medrano, J. F., Cockrum, Rebecca, Cammack, K. M., Stenmark, K. R., Moore, S., Fortes, M. R. S., Nguyen, L.T, Venus, B., Diaz, I., Souza, F., Fonseca, L., Baldi, F., Albuquerque, L., Oliveira, H., (2016) “SNP discovery in RNA-Seq across breeds of cattle in puberty-related candidate genes (i.e., network hubs)” Plant and Animal Genome Abstract PO518
  • Klohonatz, Kristin Marie, Canovas, Angela, Medrano, Juan F, Hess, Ann Marie, Coleman, Stephen John, Thomas, Milt, Bouma, Gerrit J, Bruemmer, Jason, (2016) “RNA Sequencing of equine endometrium during maternal recognition of pregnancy” Plant and Animal Genome Conference XXIV 2016
  • Jalkanen, Aimee Lynne, Coleman, Stephen John, Wilusz, Jeffrey, (2014) Determinants and implications of mRNA poly(A) tail size–does this protein make my tail look big? Seminars in cell & developmental biology 34 24-32
  • Go, Y Y, Bailey, E, Cook, D G, Coleman, Stephen John, Macleod, J N, Chen, K C, Timoney, P J, Balasuriya, U B, (2011) Genome-wide association study among four horse breeds identifies a common haplotype associated with in vitro CD3+ T cell susceptibility/resistance to equine arteritis virus infection. Journal of virology 85 24 13174-84
  • Vanderman, K S, Tremblay, M, Zhu, W, Shimojo, M, Mienaltowski, M J, Coleman, Stephen John, MacLeod, J N, (2011) Brother of CDO (BOC) expression in equine articular cartilage. Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 19 4 435-8Coleman, Stephen John, Zeng, Z, Wang, K, Luo, S, Khrebtukova, I, Mienaltowski, M J, Schroth, G P, Liu, J, MacLeod, J N, (2010) Structural annotation of equine protein-coding genes determined by mRNA sequencing. Animal genetics 41 Suppl 2 121-30

     

  • Wang, K, Singh, D, Zeng, Z, Coleman, Stephen John, Huang, Y, Savich, G L, He, X, Mieczkowski, P, Grimm, S A, Perou, C M, MacLeod, J N, Chiang, D Y, Prins, J F, Liu, J, (2010) MapSplice: accurate mapping of RNA-seq reads for splice junction discovery. Nucleic acids research 38 18 e178

     

  • Wade, C M, Giulotto, E, Sigurdsson, S, Zoli, M, Gnerre, S, Imsland, F, Lear, T L, Adelson, D L, Bailey, E, Bellone, R R, Blöcker, H, Distl, O, Edgar, R C, Garber, M, Leeb, T, Mauceli, E, MacLeod, J N, Penedo, M C, Raison, J M, Sharpe, T, Vogel, J, Andersson, L, Antczak, D F, Biagi, T, Binns, M M, Chowdhary, B P, Coleman, Stephen John, Della Valle, G, Fryc, S, Guérin, G, Hasegawa, T, Hill, E W, Jurka, J, Kiialainen, A, Lindgren, G, Liu, J, Magnani, E, Mickelson, J R, Murray, J, Nergadze, S G, Onofrio, R, Pedroni, S, Piras, M F, Raudsepp, T, Rocchi, M, Røed, K H, Ryder, O A, Searle, S, Skow, L, Swinburne, J E, Syvänen, A C, Tozaki, T, Valberg, S J, Vaudin, M, White, J R, Zody, M C, Lander, E S, Lindblad-Toh, K, (2009) Genome sequence, comparative analysis, and population genetics of the domestic horse. Science (New York, N.Y.) 326 5954 865-7

     

  • Astakhova, N M, Perelygin, A A, Zharkikh, A A, Lear, T L, Coleman, Stephen John, MacLeod, J N, Brinton, M A, (2009) Characterization of equine and other vertebrate TLR3, TLR7, and TLR8 genes. Immunogenetics 61 7 529-39

     

  • Coleman, Stephen John, Gong, G, Gaile, D P, Chowdhary, B P, Bailey, E, Liu, L, MacLeod, J N, (2007) Evaluation of Compass as a comparative mapping tool for ESTs using horse radiation hybrid maps. Animal genetics 38 3 294-302

Research Team

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Contact Us

Stephen Coleman

Assistant Professor
Director of Equine Breeding and Genetics Lab
(970) 491-2681
stephen.coleman@colostate.edu